Study Finds Patient Navigators Enhance Colonoscopy Rates Following Abnormal Stool Test Results
A recent study led by the University of Arizona Health Sciences has shed light on a crucial intervention aimed at improving the rates of follow-up colonoscopies among patients with abnormal stool test results. This research is particularly significant given the rising incidence of colorectal cancer, which remains one of the leading causes of cancer-related deaths […]

A recent study led by the University of Arizona Health Sciences has shed light on a crucial intervention aimed at improving the rates of follow-up colonoscopies among patients with abnormal stool test results. This research is particularly significant given the rising incidence of colorectal cancer, which remains one of the leading causes of cancer-related deaths in both men and women. The study provides compelling evidence that the involvement of patient navigators can meaningfully enhance the chances of individuals undergoing necessary life-saving procedures, such as colonoscopies.
The findings of this investigation were published in the esteemed journal Annals of Internal Medicine, which underscores the study’s importance in the field of public health and cancer prevention. The researchers focused on an innovative approach where patient navigators—trained professionals who assist patients in navigating the healthcare system—played a pivotal role in guiding patients through the sometimes daunting process of scheduling and preparing for a colonoscopy after receiving abnormal test results. The statistics gathered during the study are both revealing and alarming, highlighting a significant gap between those who receive appropriate follow-up care and those who do not.
The study included a randomized clinical trial with a sample size of 970 patients ranging in age from 50 to 75 years. These individuals were identified based on having recent abnormal fecal immunochemical test (FIT) results—a screening method often used to detect potential colorectal issues. The potential risk posed by these abnormal results cannot be overstated, as timely follow-up with a colonoscopy can significantly reduce the risk of progression to colorectal cancer and improve outcomes.
Among the patients who received assistance from navigators, an impressive 55% followed through with their colonoscopy within one year. In contrast, only 42.5% of patients who did not have the support of a navigator completed the procedure. This 12% increase in completion rates highlights the effectiveness of utilizing navigators as active participants in the patient’s journey toward understanding and addressing their health issues. The results suggest that when patients are equipped with personalized assistance, they are more likely to engage with their health choices and manage potentially life-threatening conditions proactively.
Gloria Coronado, PhD, the first author of the paper and the associate director of population science at the University of Arizona Cancer Center, emphasized the critical importance of rapid follow-up after abnormal results. Coronado noted that promptly arranged colonoscopies can mitigate the risks of colorectal cancer, which can be deadly if not caught early. For patients who delay obtaining the necessary care, the consequences could be dire, with studies indicating that delayed follow-up can result in a sevenfold increase in mortality rates associated with colorectal cancer.
The investigational framework known as PRECISE (Predicting and Addressing Coloscopy Non-Adherence in Community Settings) adopted in the study, was implemented at Sea Mar Community Health Centers in Washington. This initiative highlighted how federally qualified health centers could pioneer effective methods to ensure they connect their patients with essential medical services. The patient navigators employed in this project made consistent efforts to communicate with participants, which included sending letters, making phone calls, and delivering timely text messages to ensure the patients understood the procedures and importance of their upcoming colonoscopy.
The holistic support provided by these navigators included comprehensive educational approaches focused on several key subject areas: identifying barriers to care, offering emotional and logistical support, preparing patients physically for the procedure, and following up post-procedure to evaluate both stress and satisfaction levels. The patient navigators’ commitment to these tasks not only simplified the patient’s experience but potentially saved lives by ensuring that necessary screenings were not overlooked.
The outcomes of this study point to a potentially effective model for cancer prevention strategies across diverse healthcare settings. Encouraging clinics to adopt similar navigation programs could facilitate a more standardized approach for informing patients of their health status and what further action is required. By integrating systematic patient navigation, clinics can foster a culture where patients are actively engaged in their health care decisions, thereby improving overall health outcomes.
The urgent need for such interventions reflects ongoing public health challenges faced by many communities. Enhanced survival rates from colorectal cancer are attainable if systems are put in place to ensure that patients understand their health information and the crucial steps they need to take afterward. The implications of this research extend beyond single clinics or health systems; they underscore the necessity for policy changes and increased funding towards patient navigation programs nationwide.
As the study continues to gain attention, it illustrates a clear message: empowering patients with information, support, and accessibility can fundamentally change their health trajectories. By removing barriers to care and addressing patients’ concerns holistically, we may move closer to reducing the alarming rates of colorectal cancer deaths. The path forward involves increasing awareness of the tools available to enhance patient involvement and reinforcing the adequacy of follow-up care.
Moving forward, the research team advocates for broader implementation of patient navigation as an essential part of care management for those receiving abnormal stool test results. They suggest that integrating these navigators into routine cancer screening processes can create a ripple effect of improved health outcomes in populations where accessibility and adherence to recommended follow-ups, like colonoscopies, remain critical concerns.
In conclusion, the findings of this enlightening study shine a spotlight on the effectiveness of patient navigators in motivating patients to follow through with crucial cancer screenings. As healthcare providers strive to enhance the overall well-being of their patients, it is imperative to take actionable steps in implementing supportive infrastructures that include navigational support for individuals facing challenging health decisions. The evidence presented here sets a precedent not only for colorectal cancer care but for future endeavors in improving public health practices linked to cancer prevention.
Subject of Research: People
Article Title: Patient Navigation to Improve Colonoscopy Completion After an Abnormal Stool Test Result
News Publication Date: April 1, 2025
Web References: Link to study
References: DOI: 10.7326/ANNALS-24-01885
Image Credits: Photo by Kris Hanning, U of A Health Sciences Office of Communications
Keywords: Colonoscopy, Colorectal cancer, Patient navigation, Fecal immunochemical test, Healthcare intervention, Public health, Cancer prevention, Health disparities, Clinical research, Follow-up care.
Tags: abnormal stool test resultscancer-related mortality reductioncolonoscopy follow-up ratescolorectal cancer prevention strategieshealthcare system navigationimportance of colon cancer screeningimproving patient compliance in healthcarepatient education and supportpatient navigators in healthcarepublic health interventionsrandomized clinical trial findingsUniversity of Arizona Health Sciences research
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