S-Nitrosylated NEDD4 Drives Gouty Arthritis via Pyroptosis

In a groundbreaking study shedding new light on the intricate molecular pathways driving gouty arthritis (GA), researchers have unveiled how post-translational modification of a key ubiquitin ligase exacerbates disease progression by regulating a previously underexplored form of programmed cell death known as pyroptosis. This discovery not only deepens our understanding of gout’s inflammatory processes but […]

Jul 1, 2025 - 06:01
S-Nitrosylated NEDD4 Drives Gouty Arthritis via Pyroptosis
In a groundbreaking study shedding new light on the intricate molecular pathways driving gouty arthritis (GA), researchers have unveiled how post-translational modification of a key ubiquitin ligase exacerbates disease progression by regulating a previously underexplored form of programmed cell death known as pyroptosis. This discovery not only deepens our understanding of gout’s inflammatory processes but […]

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