Rewrite High-efficiency leucoplast transit peptides for manipulating plastid protein production as a headline for a science magazine post, using no more than 8 words

Plastids develop into nutrient-storing leucoplasts in seeds and roots. Efficient protein delivery is essential to modify biosynthetic processes in leucoplasts for human needs, but no effective transit peptide for leucoplasts is currently available. Here, using an in vitro leucoplast import system, we have identified six high-efficiency transit peptides. Compared with a widely used chloroplast transit […]

Jun 14, 2025 - 06:00
Rewrite High-efficiency leucoplast transit peptides for manipulating plastid protein production as a headline for a science magazine post, using no more than 8 words

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Plastids develop into nutrient-storing leucoplasts in seeds and roots. Efficient protein delivery is essential to modify biosynthetic processes in leucoplasts for human needs, but no effective transit peptide for leucoplasts is currently available. Here, using an in vitro leucoplast import system, we have identified six high-efficiency transit peptides. Compared with a widely used chloroplast transit peptide, these peptides delivered similar amounts of GFP into chloroplasts, but two to seven times more GFP into root and petal leucoplasts, attesting to the advantage of screening using leucoplasts. When used to deliver bacterial phytoene synthase (crtB) into rice calli and glyphosate-resistant EPSP synthase into Arabidopsis, these peptides enhanced carotenoid production and herbicide resistance, respectively. The correlation among levels of GFP delivery, carotenoid production and herbicide resistance indicates that the efficiency of these transit peptides is consistent across plant species and passenger proteins. Transit peptide selection therefore offers an effective way to modulate production levels of engineered proteins.

Chu, CC., Han, CY. & Li, Hm. High-efficiency leucoplast transit peptides for manipulating plastid protein production.
Nat. Plants (2025).

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bu içeriği en az 2500 kelime olacak şekilde ve alt başlıklar ve madde içermiyecek şekilde ünlü bir science magazine için İngilizce olarak yeniden yaz. Teknik açıklamalar içersin ve viral olacak şekilde İngilizce yaz. Haber dışında başka bir şey içermesin. Haber içerisinde en az 14 paragraf ve her bir paragrafta da en az 80 kelime olsun. Cevapta sadece haber olsun. Ayrıca haberi yazdıktan sonra içerikten yararlanarak aşağıdaki başlıkların bilgisi var ise haberin altında doldur. Eğer bilgi yoksa ilgili kısmı yazma.:

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Chu, CC., Han, CY. & Li, Hm. High-efficiency leucoplast transit peptides for manipulating plastid protein production.
Nat. Plants (2025). https://doi.org/10.1038/s41477-025-02020-x

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Tags: biosynthetic processes modificationengineering proteins in agricultureenhanced carotenoid productionGFP delivery in plant cellsherbicide resistance in plantshigh-efficiency leucoplast transit peptidesin vitro leucoplast import systemnutrient-storing leucoplastsplant biotechnology advancementsplastid protein productionprotein delivery in plantstransit peptide screening methods

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