Opioid cravings were reduced by anti-obesity drug in small study
Early but promising results from the first randomized controlled trial to test a popular class of weight-loss drugs against opioid addiction.
DENVER — The GLP-1 medication liraglutide significantly reduced opioid cravings in a small analysis presented on Saturday. It is the first randomized controlled trial to test anti-obesity drugs against opioid addiction, which kills around 80,000 people in the U.S. each year.
Among 20 patients for opioid use disorder, those on liraglutide experienced a 30% reduction in opioid cravings over the three-week study, with this effect evident at even the lowest liraglutide dose, according to data presented here at the American Association for the Advancement of Science conference.
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