NIH study of ME/CFS points to immune dysfunction and brain abnormalities at core of long-dismissed disease

A NIH study of myalgic encephalomyelitis, or chronic fatigue syndrome, points to immune dysfunction and brain abnormalities at the core of a long-dismissed disease.

Feb 21, 2024 - 18:00
NIH study of ME/CFS points to immune dysfunction and brain abnormalities at core of long-dismissed disease

Alison Sbrana was in the belly of an opera when her life changed. Down in the pit, surrounded by fellow orchestra members, she’d been straining to play her flute for half the show. As performers overhead enveloped the audience in arias, Sbrana felt like the Hulk was pulling on the tendons in the right side of her neck. “I begged anybody for meds at intermission,” she said.

Sbrana had contracted infectious mononucleosis, or mono, as college students do. The symptoms started during that early April performance of “Cinderella,” when Sbrana was a 20-year-old student on track for a flute career. And then the illness never went away.

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