Kennesaw State Researcher Recognized by American Heart Association for Pioneering Heart Disease Diagnostic Study

Kennesaw State University’s Chen Zhao has been awarded the prestigious American Heart Association’s Institutional Research Enhancement Award (AIREA) for 2025, a recognition that highlights groundbreaking contributions in the field of cardiovascular research. This award, amounting to $194,032, is not merely a financial boon; it represents an affirmation of the critical importance of Zhao’s research into non-invasive methods of predicting blood flow, a significant advancement in cardiovascular disease diagnosis.

Zhao’s research centers on developing innovative technology that evaluates Fractional Flow Reserve (FFR), a crucial measurement in diagnosing coronary artery disease (CAD). CAD stands as the leading cause of mortality in the United States, with the Centers for Disease Control and Prevention reporting between 375,000 to 400,000 deaths annually due to this condition. The statistics underline an urgent need for improved diagnostic methods, which is precisely the gap Zhao aims to bridge through his work.

Historically, traditional FFR measurement techniques involve invasive procedures that can be both time-intensive and costly. They often depend on computational fluid dynamics methods that may take hours to yield results. Zhao’s innovative approach intends to create a non-invasive method for evaluating FFR that dramatically shortens the evaluation time to mere seconds. This breakthrough could not only enhance the speed of diagnoses but also lessen the associated risks for patients undergoing cardiovascular evaluations.

The technology being developed by Zhao capitalizes on coronary computed tomography angiography (CCTA) scans to assess FFR. Traditional techniques involve threading a wire into the arteries to analyze pressure differentials and thereby diagnose blockages, a method fraught with risks and discomfort for the patient. By shifting to a non-invasive technique, Zhao is redefining how diagnoses can be performed, aiming ultimately for an approach that maximizes patient comfort while optimizing accuracy.

Zhao articulated the transformative potential of his research, stating that it is not merely an improvement to an existing diagnostic method but an overhaul of the entire cardiovascular diagnostic workflow. Real-time results, he suggests, could empower healthcare providers to make quicker, more informed decisions regarding patient care. This immediacy could be life-saving, emphasizing the real-world implications of his research efforts.

The accolades for Zhao’s work extend beyond its technical prowess, with Sumanth Yenduri, the Dean of the College of Computing and Software Engineering at Kennesaw State University, commending his contributions. Yenduri emphasized that Zhao’s research exemplifies the transformative capacity of interdisciplinary work, effectively merging the realms of computer science with healthcare in a way that highlights significant societal impacts.

Zhao’s fascination with cardiovascular research initiated during his doctoral studies, during which he first engaged with advanced cardiovascular imaging techniques. This early exposure ignited a desire to harness computer science in the realm of medical imaging, with the ultimate aim of refining and improving diagnostic processes. The idea to utilize CCTA for FFR prediction stemmed from a commitment to eliminating the risks associated with invasive methodologies.

The conventional approach to FFR prediction, despite its widespread use, involves significant complications. CCTA scans capture images of the coronary arteries but calculating FFR from these images using traditional computational flow dynamics methods requires extensive time and resources. Zhao recognized the potential for leveraging deep learning combined with physics-informed neural networks to revolutionize this tedious process, aiming to produce both accuracy and efficiency.

In addition to addressing current diagnostic challenges, Zhao’s vision encompasses a broader horizon. He hopes to explore the untapped potential of artificial intelligence within the realm of medical diagnostics. By refining the technologies at his disposal, he aims not only to enhance the process of diagnosing heart disease but also to potentially expand his methodologies to other medical fields.

The ultimate goal of Zhao’s research is the improvement of patient outcomes and quality of life on a global scale. He envisions a future where breakthroughs in medical imaging are commonplace, offering unprecedented advancements in diagnostics that could alter the landscape of patient care. This ambition drives his ongoing research, propelling him forward into uncharted territories of medical and technological innovation.

Zhao’s journey highlights the importance of interdisciplinary collaboration in driving meaningful advancements in health care solutions. As the fields of computer science and healthcare continue to converge, the implications of such research could pave new pathways to understanding and treating a multitude of conditions that afflict populations worldwide.

As technology continues to evolve, Zhao’s work stands at the forefront of transformative medical research. Not only is he developing methodologies and technologies that could redefine patient diagnostics, but he is also contributing to a broader narrative about the convergence of technology and medicine, hoping to inspire the next generation of researchers to explore these vital intersections.

The future of cardiovascular diagnostics may very well hinge on innovations like those being introduced by Chen Zhao. As he continues to push the boundaries of what is achievable in medical imaging, the potential benefits for countless patients around the world remain at the core of his objectives, driving his research forward with both rigor and compassion.

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Subject of Research: Non-invasive blood flow prediction in cardiovascular disease diagnostics
Article Title: Kennesaw State University’s Chen Zhao Receives 2025 AHA Award for Groundbreaking Cardiovascular Research
News Publication Date: October 2023
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Image Credits: Darnell Wilburn / Kennesaw State University

Keywords: Cardiovascular disease, Coronary artery disease, Blood flow, Medical imaging, AI in healthcare, Research enhancement, Non-invasive diagnosis, Health technology.

Tags: advancements in cardiac healthAmerican Heart Association recognitioncardiovascular disease diagnosiscoronary artery disease researchFractional Flow Reserve evaluationimproving diagnostic methodsinnovative diagnostic technologyinstitutional research enhancement awardKennesaw State University researchmortality statistics in heart diseasenon-invasive blood flow predictionreducing invasive procedures in healthcare