Izokibep by Acelyrin for Panuveitis: Likelihood of Approval
Izokibep is under clinical development by Acelyrin and currently in Phase II for Panuveitis. According to GlobalData, Phase II drugs…
Izokibep is under clinical development by Acelyrin and currently in Phase II for Panuveitis. According to GlobalData, Phase II drugs for Panuveitis does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the Izokibep LoA Report. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Izokibep overview
Izokibep (ABY-035) is under development for the treatment of posterior uveitis, panuveitis, non-infectious uveitis, intermediate uveitis, patients with moderate-to-severe plaque psoriasis, active psoriatic arthritis with inflammatory musculoskeletal disease, hidradenitis suppurativa. It is administered through subcutaneous route. ABY-035 is a IL-17A blocking molecule. It is developed based on affibody technology. Affibody molecules are antibody mimetics with superior characteristics surpassing monoclonal antibodies and antibody fragments. It was also under development for Takayasu arteritis.
It was also under development for the treatment of ankylosing spondylitis(AS).
Acelyrin overview
Acelyrin is a biopharma company that identifies, acquires and accelerates the development and commercialization of transformative medicines.It focuses on creating value for patients and shareholders. The Company’s products includes izokibep, Lonigutamab (anti-IGF-1R), XLRN-517 (anti-C-KIT). It actively investigates the potential of izokibep and other programs in diseases where differentiated therapeutic approaches are required to address unmet patient needs. It can access promising therapeutic programs through Acelyric global network of relationships across pharma and biotech, finance and academia.The company collaborates with partners, pharmaceutical companies, early-stage start-ups and academicians in identifying and developing products. It is also involved in the development of Los Angeles Biotech Hub. Acelyrin is headquartered in Agoura Hills, California, the US.
For a complete picture of Izokibep’s drug-specific PTSR and LoA scores, buy the report here.
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