Do in vivo CAR-T cell therapies have the potential to overtake ex vivo CAR-Ts?

One concern with in vivo CAR-Ts is the potential insertional mutagenesis of the lentiviral DNA payload, causing secondary cancers.

Apr 16, 2025 - 06:00
Do in vivo CAR-T cell therapies have the potential to overtake ex vivo CAR-Ts?
One concern with in vivo CAR-Ts is the potential insertional mutagenesis of the lentiviral DNA payload, causing secondary cancers.

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