DDX1 Methylation Controls MATR3 Splicing, Driving Disc Degeneration
In a pioneering study published recently in Nature Communications, researchers have unveiled a novel epigenetic mechanism that could revolutionize our understanding of intervertebral disc degeneration (IVDD), a leading cause of chronic back pain worldwide. This breakthrough hinges on the intricate molecular interplay between RNA methylation, alternative splicing, and chromatin reprogramming, with the proteins DDX1 and […]
In a pioneering study published recently in Nature Communications, researchers have unveiled a novel epigenetic mechanism that could revolutionize our understanding of intervertebral disc degeneration (IVDD), a leading cause of chronic back pain worldwide. This breakthrough hinges on the intricate molecular interplay between RNA methylation, alternative splicing, and chromatin reprogramming, with the proteins DDX1 and […]
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