12,000 diseases lack treatments. One doctor thinks generics could yield cures

Using a unique AI tool, built from a half-dozen other algorithms, Every Cure is scouring “the world’s knowledge” to figure out potential matches between FDA-approved drugs and diseases without known…

May 5, 2023 - 20:00
12,000 diseases lack treatments. One doctor thinks generics could yield cures

SAN FRANCISCO — About a decade ago, David Fajgenbaum thought his life was over. He was a young, bright physician hoping to work in oncology in remembrance of his mother, who died of brain cancer a few years earlier. Fajgenbaum was having his last rites read to him, and his family braced for his death from Castleman disease, a rare inflammatory illness that impacts the lymph nodes and can severely damage other organs.

But, in a rare stroke of skill and luck, Fajgenbaum was able to repurpose a generic drug, sirolimus, and go into remission.

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